This job post has expired on January 18, 2026. It is likely that the position has already been filled.
Buy-Side Biotech Trading Expert at Mercor
posted 9 months agoBuy-Side Biotech Trading Expert | $250–300/hr | Remote Contractor
Mercor is hiring on behalf of a frontier AI research lab building systems for high-stakes reasoning and decision-making. We're seeking candidates with buy-side biotech investing experience who combine deep scientific training with hands-on exposure to catalyst-driven biotech trading.
The ideal candidate is an MD or PhD who began their career in a biotech or pharmaceutical company and later transitioned into buy-side investing, where they evaluated and traded around clinical trial readouts and regulatory events. This role involves translating real-world investment judgment into structured, high-quality reasoning to support the development and evaluation of advanced AI systems.
Key Responsibilities
- Analyze biotech investment opportunities from a buy-side perspective
- Develop probability-weighted theses around clinical and regulatory catalysts, including Phase I–III clinical trial readouts, FDA events (PDUFAs, advisory committees, CRLs), label expansions, and competitive disclosures
- Evaluate trial design, endpoints, statistical power, and failure modes
- Translate complex clinical and regulatory data into clear, decision-ready reasoning
- Review and critique investment theses with attention to risk, uncertainty, and market impact
- Participate in post-catalyst analyses to refine frameworks and surface signal
- Collaborate with AI researchers to help benchmark and improve model performance in biotech investing tasks
Required Qualifications
- MD or PhD in medicine, life sciences, or a related field
- Prior professional experience at a biotech or pharmaceutical company
- Direct buy-side biotech experience at a hedge fund, family office, proprietary trading firm, or specialist biotech fund
- Familiarity with catalyst-driven biotech trading, including forming views around clinical readouts and FDA decisions
- Strong understanding of drug development, clinical trial processes, FDA regulatory pathways, and market reactions to biotech events
- Ability to express conviction and uncertainty in probabilistic terms
- Strong written communication skills
Preferred Experience
- Track record trading or investing around biotech catalysts
- Ability to discuss specific historical catalyst trades or investments
- Experience with event-driven or long/short biotech strategies
- Deep expertise in one or more therapeutic areas (oncology, CNS, immunology, rare disease)
- Exposure to risk sizing or position management
- Interest in applying domain expertise to AI systems
Work Arrangement
- Hourly contractor role with Mercor
- 20–30 hours per week
- Flexible, fully remote work arrangement
- Collaboration with a highly technical AI research team
Why Join
- Apply buy-side biotech investing expertise to frontier AI development
- Work on complex, real-world decision problems
- Flexible schedule and remote work
- High-impact collaboration with researchers building next-generation AI systems
How to apply for this role
- Upload your resume — keep it up-to-date and in English. Mercor will auto-fill your profile from it.
- Complete the AI interview — a 15-minute conversation about your experience. Be ready to discuss specific projects and challenges you've solved.
- Submit your application — only about 20% of applicants finish all the steps, so completing yours puts you well ahead.